Is there a self-check system in LisaScan EM?
Yes, LisaScan EM has an auto self-check future which conducts a self-check every time the instrument is started (turned on). The self-check feature will check all the major components of the instrument such as the lamp intensity, mechanics, photometer, etc., and will alert the user with a notification before conducting the assay. This feature will help the user understand the health of the instrument and take preventive action.

What types of plate geometries are compatible with LisaScan EM?
U, V and Flat bottom well plate geometries are compatible with LisaScan EM

What is the linear range of the instrument?
The linear range of the LisaScan EM is 0-2.5 OD

What is the measuring range of LisaScan EM?
The measuring range of the LisaScan EM is 0-4 OD

How many programs can be stored in LisaScan EM?
A total of 100 ELISA programs can be stored on LisaScan EM

What Filters does LisaScan EM Offer?
LisaScan EM 4 has 4 in-built filters and has the option to install 3 additional filters as well at any later stage. It comes with pre-installed filters viz. 405 nm, 450 nm, 492 nm, 630 nm filters.

Does the instrument have PC connectivity software?
Yes, Transasia offers ELI LIMS software which allows Lisa Scan EM PC connectivity

Can we connect an external printer to LisaScan EM?
Lisa Scan EM has a provision to connect a dot matrix printer directly to the instrument.

Does LisaScan EM have bi chromatic reading mode?
Yes, Lisa Scan has Monochromatic, Bi-chromatic, and multi-chromatic (up to 4 wavelengths) modes

What Operational and Calculation modes are offered on LisaScan EM?
Operational modes: Absorbance, Qualitative, Quantitative, Semi-quantitative, Kinetic
Calculation modes: Non-linear standard, cut-off, index formula, point-to-point, liner regression, cubic spline, linear–log

Does LisaScan EM have a shaker?
Yes, LisaScan EM has an inbuilt shaker with 3 adjustable speeds

What is the photometric accuracy of LisaScan EM?
Accuracy: <1 % at 2.5 OD at 450 nm
Repeatability: < 0.5% at 2.5 OD at 450 nm

How many wash programs can be stored on Erba Lisa Wash II?
50 wash protocols can be stored on Erba Lisa Wash II

How Accurate Is the washing of Erba Lisa Wash II?
Lisa Wash ll has a dispensing precision and accuracy of < 2.0% at 350µl. It has a residual volume of < 2µl thus ensuring accurate washing

How is high-precision washing achieved by Erba Lisa Wash II?

• Erba Lisa Wash II is equipped with 2-point aspiration per well which ensures minimum residual volume.
• This eliminates the risk of high background signals and ensures reliable results without compromising on analytical sensitivity.

What plate format is Erba Lisa Wash II compatible with?
Erba Lisa Wash II is compatible with U 96 well format

Does Erba Lisa Wash II have an Aerosol protection cover?
Yes

How many wash bottles are provided with Erba Lisa Wash II?
Lisa Wash II comes with 2 wash buffer bottles, 1 rinse/Dl bottle and 1 waste bottle with sensor, 2L each.

How many wash buffers can be connected at the same time?
2 wash buffer bottles can be connected at the same time

Is there a facility to prime in between wash cycles?
Yes

Does the waste bottle have a waste level sensor?

• Yes, the waste sensor helps ensure safe operations and user safety
• It also helps in avoiding backflow which may damage electronics

What is ELAN 30s?
ELAN 30s is a unique one of its kind, fully automated ELISA microwells strip processor platform, with a capacity of processing up to 6 different assays in 30 strips simultaneously.

Is ELAN 30s a benchtop instrument?
Yes, It is a compact, benchtop, walk-away true open system with, intuitive & Easy-to-use software that guides users through assay setup. A real-time run dashboard monitors assay status at all levels.

Which labs should opt for ELAN 30s?
ELAN 30s is suitable for small & mid-sized laboratories, and can also be a complement in high throughput labs for assays not available or affordable on other platforms.

How many tests can be conducted in ELAN 30s?
A total of 240 microwells can be performed in one batch.

Is ELAN 30s a batch processor or a random access processor?
ELAN 30s is a Batch processor

How many plates/strips can be processed in ELAN 30s?
As Elan 30s is a strip processor, a total of 30 strips can be processed in one batch, this can also be represented as 2.5 plates theoretically.

What ELISA processes can ELAN 30 s perform?
ELAN 30s is a fully automated Elisa Processor equipped with a single probe for dispensing samples and reagents, to the ELISA wells placed on the carousal capable of holding 30 strips. The carousel also has an incubator and shaking facility. ELAN 30s also has onboard washing and a static photometer capable of reading on dual and single wavelengths to ensure error-free readings.

How samples can be loaded on ELAN 30s?
ELAN 30s has 59 sample locations from which 18 locations can be used for reagent loading as and when required

Is there customization (Swapping of reagent bottles and tubes) available in terms of batch processing multiple assays?
ELAN 30s has dedicated slots for 12 mm × 75 mm (5ml) sample tubes, 24 × 20 ml reagent bottles, 30 × 1.5 ml calibrator/control positions, 17 additional positions for loading reagents in 5mL test tube
Thus, customization in terms of processing common batches is possible as common reagents can be kept in bigger reagent bottles and uncommon reagents can be kept separately in reagent tubes based on the requirement.

What is the dead volume required on ELAN 30s?
Reagent tubes require a minimum reagent volume of 0.5 ml in the sample and reagent tubes to perform the assay.

What if there is less reagent tube/bottle while the assay is ongoing?
The instrument undergoes a level sensing stage where all the required volumes of samples and reagents required to process the batch are checked by the instrument. Upon confirmation, that the required volume is sufficient to perform the batch, the instrument will ask permission to perform the batch.

Can the instrument detect hardware issues?
Yes, the instrument undergoes a self-check every time the instrument is turned on. During this, any error that may cause malfunction while performing the assay will be diagnosed and reported by the instrument.

What security features do ELAN 30s provide?
· Liquid level sensing before every batch
· Clot detection
· Tip detection
· Alarms

How accurate are ELAN 30s?
Elan 30s has a photometric precision of < 2% CV at 0.5 to 2.0 OD At 405nm and 450nm and an Accuracy of ± 3%OD at 0.25 OD to 2.5 OD
The washer is equipped with precise washing with a residual volume of < 5 μl
The automated pipetting arm has a Precision of < 2% CV at 10 μl and < 1% CV at 100 μl using tips

How do ELAN 30s achieve photometric accuracy?
ELAN 30s is equipped with a static photometer which moves to take the reading of each well
In conventional ELISA readers, the plate moves across and the photometer stays stationary. During the movement of the plate, there is a possibility wherein the meniscus of the well may move due to the rapid movement of the plate causing a ripple effect, and leading to erroneous results.
In ELAN 30s the plate is moved towards the photometer position and is brought to a halt which allows time for the minibus to become stationary. The photometer then moves along the strip taking readings of each well, thus ensuring higher photometric

What is Lisa XL?
Lisa XL is an advanced fully microplate processor designed to analyze all types of ELISA panels. A complete walk-away system, it can perform multiple assays per plate, thereby maximizing the efficiency of ELISA processing.

Which labs should opt for Lisa XL?
Lisa XL is ideal for high-throughput laboratories that screen a high number of samples
It is also suitable for laboratories that perform limited assays in a small-scale environment and also suitable for labs processing multiple assays with fewer sample loads

How does Lisa XL ensure minimum assay drift while performing multiple assays?
Lisa XL’s software has an intelligent timeline management function that analyses all the protocols for various assays and devices an ideal and suitable assay timeline
The high-speed robotic system on Lisa XL ensures a faster turnaround time.
Both these functions act together to ensure faster TAT and minimum assay drift.

How does Lisa XL ensure Zero carryover?
Lisa XL uses high-quality low retention disposable tips to ensure accurate dispensing which ensures zero carryovers for samples and reagents contamination.

What is the throughput of Lisa XL?
With 6 plates of 96 wells, each Lisa XL has a high throughput of processing 576 wells

Does Lisa XL have Removable racks?
Lisa Xl has 20 removable and interchangeable reagent racks for quickset-up
A removable reagent rack can be loaded just once, and reused in subsequent runs for the same assays, thus reducing set-up time

Can Lisa XL process whole blood samples?
It is the only analyzer in India that processes serum and whole blood simultaneously

What is the onboard reagent capacity of Lisa XL?
In one run, 20 racks of 16 samples or reagents can be loaded interchangeably, for high-volume testing.

How many plates can be processed on Lisa XL at the same time?
Six independent plates of 96 wells can be processed at the same time in a single batch in Lisa XL

What is the sample capacity of Lisa XL?
Lisa XL allows running multiple parameters for over 250 samples in a single batch

How many buffers can be loaded on Lisa XL?
6 independent buffer bottles with a capacity of holding 2.25 litters independently can be loaded on Lisa XL

Does the instrument have continuous loading?
Two batches can be simultaneously loaded on Lisa XL.

How many probes are in Lisa XL?
Lisa XL has 2 probes that are capable of high-speed pipetting of reagents and samples.

How many incubators are in Lisa XL?
Lisa XL has 6 independent incubators
Each incubator can incubate between temperatures of 5°C-50°C
Each incubator has an inbuilt orbital shaker with shaking speeds of 200 to 800 RPM and adjustable time

Can we program multiple assays on the same plate?
Up to 12 assays can be programmed on the same plate.

How does Lisa XL Ensure accurate washing?
Lisa XL has a Super Sweep Mode for superior washing
A 16-channel automatic well washer rapidly performs strip-wise/plate-wise wash cycles. Multi-point aspiration ensures superior washing with a minimal residual volume of 5µl.

What process Securities does Lisa XL have?
Lisa Xl is equipped with process security features such as Liquid level sensing, Well fill verification, Clot detection, On-board sample identification, Onboard reagent identification, Strip verification, Buffer sensing, and Alarms

Which filter Lisa XL has for photometric readings?
Lisa XL has 8 Position filter wheel equipped with 405 m, 450 nm, 492 nm, 620 nm standard filters and an option to upgrade to 578 nm & 700 nm optional + 2 open

What is the linearity of the instrument?
Up to 3 OD at 450 nm

What is the washing precision of Lisa Xl?
< 5% at 300µl

How does Lisa XL ensure accurate Washing?
Lisa XL has a floating head coupled with a super sweep mode 

What is the principle of Laura SMART system?
Laura SMART works on Reflectance photometry
 
Is Laura SMART an open system? 
It is compatible with Erba Lachema strips only.
 
Is Laura SMART a replacement for Visual Microscopy?
Laura Smart as any other Urine analyzer performs Urine Chemistry tests.  Laura Smart is meant for routine screening of urine samples for chemistry tests. 
 
Does this system require daily calibration by the user?
Laura SMART does not require daily calibration. 
 
What maintenance is required daily for Laura SMART reader?
Cleaning of strip loader with dry tissue regularly
 
Does Laura SMART automatically read different strips from Ebra Lachema?
Yes, it automatically reads the strips without changing any settings.
 
Does Laura SMART automatically calculate the albumin-creatinine ratio?
Yes it calculates the ACR ratio automatically by using special algorithms
 
Does LAURA SMART have LIS capabilities?
Yes, LIS connectivity is possible.

What is the principle of Laura system?

Laura works on Reflectance photometry

 

Is Laura an open system? 

It is compatible with Erba Lachema strips only.

 

Is Laura a replacement for Visual Microscopy?

Laura like any other Urine analyzer performs Urine Chemistry tests. Laura is meant for routine screening of urine samples for chemistry tests. 

 

What is the major difference between Laura SMART & Laura new version?

Laura SMART is single strip reader whereas Laura new version is a continuous loading system for higher throughput 

 

Does this system require daily calibration by the user?

Laura does not require daily calibration. 

 

What maintenance is required daily for Laura analyzer?

Cleaning of attached waste bin & conveyor belt regularly

 

Does Laura automatically read different strips from Erba Lachema?

Yes, it automatically reads the strips without changing any settings.

 

Does Laura automatically calculate the albumin-creatinine ratio?

Yes it calculates the ACR ratio automatically by using special algorithms

 

Does LAURA have LIS capabilities?

Yes, LIS connectivity is possible.

 

 

What is the technology of LAURA® XL system?
LAURA® XL system Automated bright field microscopy (digital microscopy) for sediment analysis, Reflectance photometry for Urine chemistry, and AI (Artificial intelligence) for reading slides, and comparing chemistry and microscopy results.
 
Is LAURA® XL an open system? 
It is compatible with Erba Lachema strips only.
 
Is LAURA® XL a replacement for Visual Microscopy?
Yes, Laura XL simulates visual microscopy on a digital platform, providing high-quality images for reviewing later.
 
Is it possible to share sediment images with the report?
Images of sediment can be shared separately via USB or email. 
 
What maintenance is required daily for the LAURA® XL system?
Daily maintenance can be scheduled automatically on an instrument for cleaning.
 
How is the onboard stability of the urine strip extended?
Active humidity control system present inside the system with help of a humidifier
 
Does LAURA® XL flag any discrepancy between strip chemistry and sediment result?
Yes, it does flag any discrepancy between chemistry & sediment for parameters
 
Does LAURA® XL have LIS capabilities?
Yes, Bi-directional LIS connectivity is possible.
 
What are the consumables for Laura XL system?
Strips, Distilled water & Cleaning solution concentrates.
 
Is the system display a touch screen?
Yes, the system has a Multi-touch screen

What is HbA1c?

HbA1c is Glucose attached at N terminal of the β-chain of Hemoglobin.

 

What is the Clinical Value of “A1c” or the key benefits of the Hemoglobin A1c assay (HbA1c)?

The clinical value of HbA1c is in the Diagnosis and monitoring of type 2 Diabetes

The key benefits of the assay are as follows:

HbA1c is an index of long-term Glucose Control (90-120 days)

                                 Test Results are not affected by,

Time of the Day

Meal Intake

Exercise

Just Administered Diabetes Drugs

Emotional Stress

Correlates to complications

Improved accuracy to the international reference system, IFCC.

Standardization with the National Glycohemoglobin Standardization Program (NGSP)

 

Are there standard result units available with the Hemoglobin A1c assay?

Yes, the HbA1c assay provides the choice of reporting results in either % or mmol/mol in alignment with the ADA/EASD/IFCC/IDF Consensus Statement on the Worldwide Standardization of the HemoglobinA1c Measurement.

 

Should I report HbA1c results in % or mmol/mol? 

Many countries in the European Union, and elsewhere, have decided to adopt the SI unit [mmol/mol] for reporting HbA1c results. In the US, the American Diabetes Association (ADA) has not indicated plans to move away from the currently used result unit (%). You may report as per the needs of your clinician.

 

What is IFCC , DCCT,NGSP& ADA ?

 IFCC : International Federation of Clinical Chemistry 

 DCCT : Diabetes Control and Complication Trial.

NGSP : National Glycohemoglobin Standardization Program

ADA   :  American Diabetes Association

 

Is the HbA1c assay approved for the diagnosis of diabetes?

Yes, Since 2010, ADA recommends HbA1c for the diagnosis of diabetes.

 

 

Should I report the Estimated Average Glucose in addition to the Hemoglobin A1c value?

 In the 2010 Standards of Medical Care in diabetes, the American Diabetes Association (ADA) has recommended: “reporting both an HbA1c and an estimated Average Glucose (eAG) result when a clinician orders the HbA1c test.”

 

What is the Sample Stability for HbA1c testing?

Samples should be collected in a vacuum collection tube containing EDTA. Sample stable for 7 days at 2-8C and 3 days at room temperature (15-30oC)

 

What is the assay range for % [mmol/mol] HbA1c?

The HbA1c assay has a measurement range is 3.5 – 18.0 % [17.67 – 173.2 mmol/mol]

 

What calibrator should I use to calibrate the HbA1c assay?

Use the HbA1c calibrator included in the Hb-Vario/ Hb820 HbA1c kit to calibrate the HbA1c assay. The calibrator and reagent are a matched set and must be used together.